2-Bromoethanol → US9663460, Example 5

HRID 70391Notes

Reaction equation

HRID 70391 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].Br[CH2:11][CH2:12][OH:13].[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][C:16]=1[C:25]([F:28])([F:27])[F:26]>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([NH:1][C:2]2[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=2[S:9][CH2:11][CH2:12][OH:13])(=[O:22])=[O:23])=[CH:17][C:16]=1[C:25]([F:28])([F:26])[F:27]

Participants

4

Reactant 3

HCID 108982-BromoethanolHCID 120002-Amino-4-chlorobenzenethiolHCID 27807194-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride

Product 1

HCID 67973143US9663460, Example 5

Procedure

Following General Procedure A and B, the title compound was prepared from 2-amino-4-chloro-benzenethiol, 2-bromo-ethanol, and 4-chloro-3-(trifluoromethyl)benzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-2922f043bfbd443a9261e6e0ee7aad66
Source dataset
uspto-grants-2014_09
Patent number
US08822530B2

Reaction notes

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