Potassium Fluoride → HCID 22149754, compound

Participants

Reaction Steps

Into a 1 l glass reactor equipped with a condenser, 291 g (1 mol) of 2,2,2-trifluoroethyl 2,4-dichloro-5-fluorobenzoate, 87 g (1.5 mol) of spray dried potassium fluoride and 500 g of sulforane were charged and reacted at 180° C. for 9 hours under vigorous stirring. After cooling, the inorganic salt was removed by filtration, and the filtrate was distilled under reduced pressure to obtain 239.4 g (yield: 87.2%) of 2,2,2-trifluoroethyl 2-chloro-4,5-difluorobenzoate.

Provenance & Evidence