HRID7043

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID86996

Benzonitrile, 4-(bromomethyl)-

C8H6BrN

结构：NC(=O)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccc(Cl)cc1

HCID69656245

未命名化合物

PRODUCTS

生成物

结构：N#Cc1ccc(CN([C@@H]2CCCC[C@H]2C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1

HCID11247468

未命名化合物

收率 43%

PROCEDURE

实验过程

The titled compound was prepared in 43% yield from trans-2-(4-chlorobenzenesulfonylamino)-cyclohexanecarboxylic acid amide and 4-bromomethyl-benzonitrile according to the procedure described in Example 11: 1H NMR (DMSO-d6) δ 7.71(m, 4 H), 7.53 (m, 4 H), 7.29 (s, 1 H), 6.76 (s, 1 H), 4.44 (AB2,2 H,Δv=16,Jab=84 Hz), 3.96 (m, 1 H), 1.80 (m, 1 H), 1.57 (m, 3 H), 1.17 (m, 5 H); MS m/e 432.01 (M+H)+.