Hydrochloric Acid → HCID 67519956, compound

HRID 704312Notes

Reaction equation

HRID 704312 reaction equation
[ClH:1].[S:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[NH:7][CH2:8][C:9]([OH:11])=[O:10].[CH3:12]O>>[ClH:1].[S:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[NH:7][CH2:8][C:9]([O:11][CH3:12])=[O:10]

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 887Methanol2×HCID 21071957HCID 21071957, compound

Product 1

HCID 67519956HCID 67519956, compound

Conditions

Temperature
50 °C

Procedure

Gaseous HCl is passed into a solution of 6.8 g of 2-thienylaminoacetic acid in 70 ml of methanol, and the mixture is heated at 50° C. for 6 h. The excess methanol and hydrochloric acid are stripped off in vacuo, and the solid residue is washed with methanol and dried in vacuo.

Workup

  1. washthe solid residue is washed with methanol
  2. customdried in vacuo

Sources & evidence

ORD record
ord-93e5fcc07e07432193e8ee6978eeca23
Source dataset
uspto-grants-1991_01
Patent number
US04987134

Reaction notes

Loading…