Sodium Hydroxide → 3-Hydroxy-N-isopropylbenzenesulfonamide

HRID 704324Notes

Reaction equation

HRID 704324 reaction equation
[CH3:1][CH:2]([NH:4][S:5]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14]C(=O)C2C=CC=CC=2)[CH:9]=1)(=[O:7])=[O:6])[CH3:3].[OH-].[Na+]>O1CCCC1>[CH3:3][CH:2]([NH:4][S:5]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([OH:14])[CH:9]=1)(=[O:7])=[O:6])[CH3:1]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 200741991-[N-(Prop-2-yl)sulphamoyl]-3-(benzoyloxy)benzene

Product 1

HCID 157296513-Hydroxy-N-isopropylbenzenesulfonamide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of the product of stage 2 (0.18 g), 2M aqueous sodium hydroxide solution (15 cm3) and tetrahydrofuran (15 cm3) was stirred for 2 hours at the ambient temperature.

Sources & evidence

ORD record
ord-8b1b831dadaf425ca57df36ea85c9766
Source dataset
uspto-grants-1991_01
Patent number
US04987141

Reaction notes

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