Glycolic Acid → Acetic acid, 2-hydroxy-, compd. with 5-amino-1H-1,2,4-triazole-3-methanol (1:1)

HRID 704490Notes

Reaction equation

HRID 704490 reaction equation
[C:1]([OH:5])(=[O:4])[CH2:2][OH:3].NO[C:8]([NH:10][C:11]([NH2:13])=[NH:12])=O.[N+:14]([O-])(O)=O>>[C:1]([OH:5])(=[O:4])[CH2:2][OH:3].[NH2:13][C:11]1[N:10]=[C:8]([CH2:1][OH:5])[NH:14][N:12]=1

Participants

4

Reactant 3

HCID 757Glycolic AcidHCID 944Nitric AcidHCID 178513113HCID 178513113, compound

Product 1

HCID 222696Acetic acid, 2-hydroxy-, compd. with 5-amino-1H-1,2,4-triazole-3-methanol (1:1)

Procedure

While stirring 1738 g (16 moles) of a 70% glycolic acid, 1088 g (8 moles) of aminoguanidino-carboxylic acid was added thereto with little by little. To the mixture was added 8 ml of conc. nitric acid and the mixture was stirred under reflux for 24 hours. The reaction mixture was ice-cooled, and then precipitates were collected by filtration, washed with water and then dried.

Workup

  1. additionwas added
  2. temperatureunder reflux for 24 hours
  3. temperaturecooled
  4. customprecipitates
  5. filtrationwere collected by filtration
  6. washwashed with water
  7. customdried

Sources & evidence

ORD record
ord-31061cdbac024770bcfc5b2e7876ff51
Source dataset
uspto-grants-1991_01
Patent number
US04987129

Reaction notes

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