HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 2-(((2-amino-4-fluorophenyl)thio)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-(bromomethyl)benzoate | HCID 2734813 | — |
| Reactant | 2-Amino-4-fluorobenzene-1-thiol | HCID 11105480 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2-(((2-amino-4-fluorophenyl)thio)methyl)benzoate | HCID 82976415 | 63.1% |
Reaction Steps
Following General Procedure A, the title compound (1.8 g, 60%) was prepared from 2-amino-4-fluorobenzenethiol (1.4 g, 9.79 mmol) and methyl 2-(bromomethyl)benzoate (2.2 g, 9.79 mmol), K2CO3 (4.0 g, 29.4 mmol) in DMF (50 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-e780acc0b94e4d068728336494a66a11 |
| Source note | uspto-grants-2014_09 |