HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 3-(((2-amino-4-fluorophenyl)thio)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
| Reactant | 2-Amino-4-fluorobenzene-1-thiol | HCID 11105480 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 3-(((2-amino-4-fluorophenyl)thio)methyl)benzoate | HCID 43304147 | 88.2% |
Reaction Steps
Following General Procedure A, the title compound (750 mg, 88%) was prepared from 2-amino-4-fluorobenzenethiol (417 mg, 2.92 mmol) and methyl 3-(bromomethyl)benzoate (666 mg, 2.92 mmol), K2CO3 (1.21 g, 8.75 mmol) in DMF (10 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2f921ff9439247f9bddfed1b2e31811a |
| Source note | uspto-grants-2014_09 |