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HRID70455

反应详情

EQUATION

反应方程式

HRID 70455 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：COC(=O)c1cccc(CBr)c1
HCID517981

Methyl 3-(bromomethyl)benzoate

C9H9BrO2

结构：Nc1cc(F)ccc1S
HCID11105480

2-amino-4-fluorobenzene-1-thiol

C6H6FNS

PRODUCTS

生成物

1
结构：COC(=O)c1cccc(CSc2ccc(F)cc2N)c1
HCID43304147

未命名化合物

收率 88.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Following General Procedure A, the title compound (750 mg, 88%) was prepared from 2-amino-4-fluorobenzenethiol (417 mg, 2.92 mmol) and methyl 3-(bromomethyl)benzoate (666 mg, 2.92 mmol), K2CO3 (1.21 g, 8.75 mmol) in DMF (10 ml).