Sodium Hydroxide → HCID 9815420, compound

Participants

Reaction Steps

To a solution of sodium hydroxide (0.1 mol) at 80° C. is added N-[[[4-(1-pyrrolidinyl)-2-butynyl]amino]-carbonyl]-benzamide (4.3 g, 0.015 mol) (Example 1f) in one portion. The solution is allowed to stir for 12 minutes, cooled, extracted with chloroform, dried over magnesium sulfate and concentrated to give an oil which solidifies upon standing; mp 71°-73° C.

Provenance & Evidence