HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 704557Generated: October 30, 2026
Benzylamine → 1-methyl-5-phenyl-3-{(phenylmethyl)-amino}-1H-1,5-benzodiazepine-2,4(3H, 5H)-dione
https://huagongshe.com/reaction/704557
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 3-bromo-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4-(3H, 5H)-dione | HCID 14697658 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-methyl-5-phenyl-3-{(phenylmethyl)-amino}-1H-1,5-benzodiazepine-2,4(3H, 5H)-dione | HCID 14697659 | — |
Reaction Steps
A mixture of 50 mg of the product of Step B and 2 ml of benzylamine was heated at 100° C. for 3 hours and the reaction medium was poured into water. The product obtained was separated, washed, and dried in the presence of phosphoric anhydride to obtain 50 mg of the sought product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04988692 |
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| Source dataset | uspto-grants-1991_01 |
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| ORD ID | ord-eedb9b22640b40bb8f4133c725dde4e3 |
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| Source note | uspto-grants-1991_01 |
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