HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 4-(((2-amino-4-fluorophenyl)thio)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| Reactant | 2-Amino-4-fluorobenzene-1-thiol | HCID 11105480 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 4-(((2-amino-4-fluorophenyl)thio)methyl)benzoate | HCID 43304285 | 94% |
Reaction Steps
Following General Procedure A, the title compound (873 mg, 94%) was prepared from 2-amino-4-fluorobenzenethiol (456 mg, 3.19 mmol) and methyl 4-(bromomethyl)benzoate (731 mg, 3.19 mmol), K2CO3 (1.32 g, 9.58 mmol) in DMF (20 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822530B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-1ffbd800034d43a988149fe8aef05e05 |
| Source note | uspto-grants-2014_09 |