HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-m-cresol → 1-(4-Hydroxy-2-methylphenyl)-2,3-dihydropyrrolo[3,2-c]-cinnoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-m-cresol | HCID 17819 | — |
| Reactant | 4-Chloro-3-(2-chloroethyl)cinnoline | HCID 20072752 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-(4-Hydroxy-2-methylphenyl)-2,3-dihydropyrrolo[3,2-c]-cinnoline hydrochloride | HCID 20072755 | — |
Reaction Steps
4-Chloro-3-(2-chloroethyl)cinnoline (1 g, 0.0044 mol) and 4-hydroxy-2-methylphenylamine (0.54 g, 0.0044 mol) in 1,4 dioxan (20 ml) were heated under reflux for 20 hours. The solid obtained was collected by filtration and dried. Recrystallization from ethanol gave the title compound, 0.4 g, m.p. >300°
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04988695 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-a1afc8196a0f48aaa3b96050e5d8c96b |
| Source note | uspto-grants-1991_01 |