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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 704840Generated: October 30, 2026

alpha-Chloro-o-xylene → 4-Chloromethylbenzocyclobutene

https://huagongshe.com/reaction/704840

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Chloro-o-xyleneHCID 11093—
Reactant4-ChloromethylbenzocyclobuteneHCID 12617718—
Product4-ChloromethylbenzocyclobuteneHCID 12617718—
ProductHCID 131716734HCID 131716734—

Reaction Steps

Preparation of 4-chloromethylbenzocyclobutene was also effected by a similar procedure beginning with o-methylbenzyl chloride, however, the procedure yielded about a 1:2 mixture of 3-chloromethylbenzocyclobutene and 4-chloromethylbenzocyclobutene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04988770
Source datasetuspto-grants-1991_01
ORD IDord-a864e9e64955418dbd62d7abe3b1ccdc
Source noteuspto-grants-1991_01