反应详情

3-Amino-3-methyl-1-butanol (20.60 g, 0.20 mol) was added to ethyl formate (29.60 g, 0.40 mol), and the resulting clear solution was heated to reflux under nitrogen for 2 hours, and then allowed to cool to room temperature. The ethyl formate and ethanol by-product were removed by rotary evaporation (35° C., 25 Torr). The resulting oil was dried under vacuum (25° C., 0.1 Torr) to yield 25.86 g (99%).

1. temperaturethe resulting clear solution was heated
2. temperatureto reflux under nitrogen for 2 hours
3. customThe ethyl formate and ethanol by-product were removed by rotary evaporation (35° C., 25 Torr)
4. customThe resulting oil was dried under vacuum (25° C., 0.1 Torr)
5. customto yield 25.86 g (99%)