反应详情

190 mg (0.5 mmol) of HATU, 70 mg (0.5 mmol) of HOAt, 152 mg (0.5 mmol) of Boc-Glu-OtBu hydrochloride, 0.21 mL (1.5 mmol) of triethylamine and 2 mL of dichloromethane were added to 110 mg (0.5 mmol) of methyl 2,5-dichloro-3-aminobenzoate, and stirred at room temperature overnight.