Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Propanol | HCID 1031 | — |
| Reactant | 6-(1H-Imidazol-1-yl)-2-phenylquinazoline | HCID 24898732 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 49856399 | HCID 49856399 | — |
Reaction Steps
50 mg of 6-(1H-imidazol-1-yl)-2-phenylquinazoline are suspended in 4 mL of isopropanol, the suspension is heated at 70° C. for a few minutes, and then filtered and left to evaporate slowly at room temperature, at rest. The crystals obtained are analysed. XRPD: Form B. TGA: weight loss: 6.8% (theoretical value for C17H12N4.H2O: 6.2%), TGA-IR in accordance with the spectrum of H2O for the released vapours. Form B may be obtained analogously from n-propanol and from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09174966B2 |
|---|
| Source dataset | uspto-grants-2015_11 |
|---|
| ORD ID | ord-a7bc8ae1039b41e790b95ac5de2946bb |
|---|
| Source note | uspto-grants-2015_11 |
|---|
