Ethyl butyrate → HCID 10057613, compound

HRID 705830Notes

Reaction equation

HRID 705830 reaction equation
C[C:2](C)([O-:4])C.[K+].[C:7]([O:12][CH2:13][CH3:14])(=[O:11])[CH2:8][CH2:9][CH3:10]>C1COCC1.C(OCC)C>[OH:4]/[CH:2]=[C:8](\[CH2:9][CH3:10])/[C:7]([O:12][CH2:13][CH3:14])=[O:11]

Participants

5

Reactant 2

HCID 7762Ethyl butyrateHCID 23665647Potassium tert-butoxide

Product 1

HCID 10057613HCID 10057613, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 8028TetrahydrofuranSolvent

Procedure

To a suspension of potassium tert-butoxide (3.86 g, 34.4 mmol) in THF (20 mL) under nitrogen at room temperature was added a solution of ethyl butanoate (2.275 mL, 17.22 mmol) in diethyl ether (20.0 mL). The reaction mixture was stirred at rt for 3 hrs. The mixture was quenched and concentrated to give the title compound. LCMS: rt=2.34 min, [M+H+]=143

Workup

  1. customThe mixture was quenched
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-56fe09ac27c34de79c48c9be645bed44
Source dataset
uspto-grants-2015_11
Patent number
US09174968B2

Reaction notes

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