HRID706017
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 130 °C
PROCEDURE
实验过程
To a suspension of methyl (2Z)-3-hydroxy-2-[(1-methyl-1H-pyrazol-4-yl)methyl]-2-propenoate (125 mg, 0.636 mmol) and 2-(4-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-phenyl)ethyl imidocarbamate (190 mg, 0.530 mmol) in toluene (4 mL) was added K2CO3 (220 mg, 1.589 mmol). The mixture was heated with a microwave reactor at 130° C. for 1 h. Purification via MDAP then afforded the title compound (55 mg, 16.78% yield). LCMS: rt=3.45 min, [M+H+]=505
WORKUP
后处理
- customPurification via MDAP