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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 707146Generated: October 29, 2026

Glycine methyl ester hydrochloride → HCID 44546614, compound

https://huagongshe.com/reaction/707146

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine methyl ester hydrochlorideHCID 122755—
ReactantHCID 86636772HCID 86636772—
CatalystTriethylamineHCID 8471—
ProductHCID 44546614HCID 44546614—

Reaction Steps

Starting from 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(4-oxopiperidin-1-yl)-1,3,5-triazin-2-yl)phenyl)-3-(pyridin-4-yl)urea-TFA (50 mg) and glycine methyl ester hydrochloride (20 mg) and triethylamine (10 drops) and following the procedure as outlined in example 118 the title compound was isolated as its di-TFA salt after HPLC purification; MS (ES+) 574.8 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09174963B2
Source datasetuspto-grants-2015_11
ORD IDord-575729723f9a47a8ae5123f565b3b2c4
Source noteuspto-grants-2015_11