Hydrochloric Acid → HCID 178478747, compound

Participants

Reaction Steps

A solution of tert-butyl(cis-3-(benzo[d]thiazol-2-ylamino)cyclobutyl)carbamate (0.40 g, 1.252 mmol) in Dioxane (5 mL) was treated with hydrogen chloride, 4N in 1,4-dioxane (6.26 ml, 25.05 mmol). The resulting solution was stirred at room temperature for 2 h and concentrated to give the desired product cis —N1-(benzo[d]thiazol-2-yl)cyclobutane-1,3-diamine dihydrochloride (0.301 g, 1.030 mmol, 82% yield). 117243-44-1. The product was used in next step without further purification. m/z: 220.1 (M+1) (−2HCl)

Provenance & Evidence