HCID 86694247, compound → HCID 86694248, compound

Participants

Reaction Steps

A solution of ethyl 2-(2-chloropyridin-3-yl)-2-hydroxypropanoate (0.2 g, 0.871 mmol) in hydrochloric acid, 37% (Sigma Aldrich, 2.75 ml, 33.5 mmol) was heated in a sealed tube at 60° C. overnight. Reaction mixture was rotovapped and dried by vacuum pump. The residue containing 2-(2-chloropyridin-3-yl)-2-hydroxypropanoic acid was advanced to next step. M: 201.9.

Provenance & Evidence