Sodium Carbonate → HCID 86706842, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 2-methyl-5-formyl-pyrimidine (180 gm) and hydroxylamine hydrochloride (128 gm) in 50% v/v aqueous methanol (3600 ml) was added sodium carbonate (94 gm). The reaction mixture was stirred at 30° C. for 0.5 h. The resulting suspension was cooled and filtered at −10° C. to provide single isomer of title compound in 113.5 gm quantity (56%) as a solid.

Provenance & Evidence