Sodium Bicarbonate → HCID 118379355, compound

Participants

Reaction Steps

Prepared in an anologous manner to example 85, step 4 using 3-((((2-(((2R,3S)-3-((Z)-2-((1-((benzhydryloxy)carbonyl)cyclopropoxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-4-oxoazetidin-2-yl)methyl)-2H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1-methylpyridin-1-ium chloride (50 mg, 0.058 mmol), Boc-anhydride (0.027 mL, 0.115 mmol), NaHCO3 (satd aq, 1.22 mL) and DCM (1.15 mL). LCMS: Rt=0.99 min, m/z=921.3 (M+) Method 2m_acidic.

Provenance & Evidence