Acetic Anhydride → N-(6-methyl-5-nitropyridin-2-yl)acetamide

HRID 708599Notes

Reaction equation

HRID 708599 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12](OC(=O)C)(=[O:14])[CH3:13]>>[CH3:1][C:2]1[N:7]=[C:6]([NH:8][C:12](=[O:14])[CH3:13])[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 2479766-Methyl-5-nitropyridin-2-amine

Product 1

HCID 4072726N-(6-methyl-5-nitropyridin-2-yl)acetamide

Procedure

6-Methyl-5-nitro-pyridin-2-ylamine (1.0 g) was treated with acetic anhydride according to General Procedure Y to give N-(6-Methyl-5-nitro-pyridin-2-yl)-acetamide (1.2 g).

Sources & evidence

ORD record
ord-59ed22f78aa8455b8d5662728f857577
Source dataset
uspto-grants-2015_11
Patent number
US09175003B2

Reaction notes

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