Hydrochloric Acid → HCID 118093112, compound

Participants

Reaction Steps

17F (2.566 g, 7.12 mmol) was dissolved in dichloromethane (40 mL), then HCl (4M in dioxane) (10 mL, 40.0 mmol) was added. The reaction mixture was stirred for 1 h at rt. The solvent was removed under reduced pressure, and the residue was dried under high vacuum to give 17G (2.265 g, 6.80 mmol, 95% yield) as an off-white solid. MS (ESI) m/z: 261.1 [M+1]+. 1H NMR: (400 MHz, CD3OD) δ ppm 7.30-7.53 (7H, m), 5.33 (2H, s), 4.07 (2H, s), 2.65 (3H, s).

Provenance & Evidence