Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709035Generated: October 30, 2026

Isoxazole, 4-(chloromethyl)-3,5-dimethyl- → 5-{[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/709035

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoxazole, 4-(chloromethyl)-3,5-dimethyl-HCID 88246—
Reactant5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731527—
Product5-{[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731530—

Reaction Steps

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 3,5-dimethyl-4-chloromethyl-1,2-oxazole instead of 1-(chloromethyl)-4-ethylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-b4f888ebae0b40d48c7104b1a137b589
Source noteuspto-grants-2015_11