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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709036Generated: October 30, 2026

4-(Chloromethyl)-2-methyl-1,3-oxazole → 3-(Methoxymethoxy)-1-(methoxymethyl)-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}pyridin-2(1H)-one

https://huagongshe.com/reaction/709036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-2-methyl-1,3-oxazoleHCID 21698321—
Reactant5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731527—
Product3-(Methoxymethoxy)-1-(methoxymethyl)-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}pyridin-2(1H)-oneHCID 86731531—

Reaction Steps

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 2-methyl-4-chloromethyl-1,3-oxazole instead of 1-(chloromethyl)-4-ethylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-fc5f14cee9d54edab19933bd7ca250c7
Source noteuspto-grants-2015_11