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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709039Generated: October 29, 2026

5-Chloro-2-(chloromethyl)pyridine → 5-{[(5-Chloropyridin-2-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/709039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-(chloromethyl)pyridineHCID 14517151—
Reactant5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731527—
Product5-{[(5-Chloropyridin-2-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731534—

Reaction Steps

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 2-chloromethyl-5-chloropyridine instead of 1-(chloromethyl)-4-ethylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-e7287ba653534dd3afc3bfb319fb587d
Source noteuspto-grants-2015_11