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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709049Generated: October 29, 2026

3-Iodotoluene → 3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/709049

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IodotolueneHCID 12268—
Reactant2,3-Dimethoxy-5-[(2-methylphenyl)ethynyl]pyridineHCID 71186209—
Product3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-oneHCID 71187170—

Reaction Steps

Prepared as described for 2,3-dimethoxy-5-[(2-methylphenyl)ethynyl]pyridine (Intermediate 33) but using 1-iodo-3-methylbenzene instead of 1-iodo-2-methylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-13e57c047eee4688be8fdd41aa1f07b2
Source noteuspto-grants-2015_11