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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709123Generated: October 30, 2026

HCID 58012296, compound → HCID 58011728, compound

https://huagongshe.com/reaction/709123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58012296HCID 58012296—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 58011728HCID 58011728—

Reaction Steps

1.035 g (2.54 mmol) of ethyl 3-{[(benzyloxy)carbonyl]amino}-2-[2-(trifluoromethyl)phenyl]propanoate [for the preparation see Example 193A in WO 2007/134862] were dissolved in 24 ml of ethanol and hydrogenated in the presence of 100 mg of 10% palladium on carbon for 3 h at atmospheric pressure. The catalyst was then filtered off and the filtrate was freed from the solvent on a rotary evaporator. The residue corresponded to the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180120B2
Source datasetuspto-grants-2015_11
ORD IDord-96d2772fb3d74bc9a6280f7cdc63f1ec
Source noteuspto-grants-2015_11