HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58012296, compound → HCID 58011728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58012296 | HCID 58012296 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58011728 | HCID 58011728 | — |
Reaction Steps
1.035 g (2.54 mmol) of ethyl 3-{[(benzyloxy)carbonyl]amino}-2-[2-(trifluoromethyl)phenyl]propanoate [for the preparation see Example 193A in WO 2007/134862] were dissolved in 24 ml of ethanol and hydrogenated in the presence of 100 mg of 10% palladium on carbon for 3 h at atmospheric pressure. The catalyst was then filtered off and the filtrate was freed from the solvent on a rotary evaporator. The residue corresponded to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09180120B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-96d2772fb3d74bc9a6280f7cdc63f1ec |
| Source note | uspto-grants-2015_11 |