Hydrochloric Acid → HCID 89764462, compound

Participants

Reaction Conditions

Reaction Steps

105 mg (0.27 mmol) of the compound of Example 19A were dissolved in 2 ml of a 4 N solution of hydrogen chloride in dioxane, and the mixture was stirred at 60° C. until the reaction had gone to completion (about 2 h). The volatile components were then removed on a rotary evaporator and the residue was dried under high vacuum. This gave 91 mg of the title compound in a purity of about 83% according to LC/MS (about 86% of theory); this material was reacted further without further purification.

Provenance & Evidence