3-Methylbenzylamine → HCID 10785436, compound

HRID 709342Notes

Reaction equation

HRID 709342 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][NH2:6]>[Pd].CC#N>[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][NH:6][CH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:4]([CH3:5])[CH:3]=1

Participants

4

Reactant 1

HCID 660153-Methylbenzylamine

Product 1

HCID 10785436HCID 10785436, compoundYield 90%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 6342AcetonitrileSolvent

Conditions

Temperature
90 °C

Procedure

3-Methylbenzylamine (0.5 mmol) was heated with catalyst Pd@ba-GO (10 mg) and solvent CH3CN (0.2 mL) at 90° C. in a flask open to air for 6 hours, and then stirred also at 90° C. under H2 gas (1 atm) for 8 hours to obtain di-(3-methylbenzyl)amine. An unexpectedly high yield of 90% was observed.

Sources & evidence

ORD record
ord-25751c398aed468893b5bca764be17b4
Source dataset
uspto-grants-2015_11
Patent number
US09180442B2

Reaction notes

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