2-Methylbenzylamine → HCID 19843001, compound

HRID 709343Notes

Reaction equation

HRID 709343 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH2:5]>[Pd].CC#N>[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH:5][CH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH3:4]

Participants

4

Reactant 1

HCID 69932-Methylbenzylamine

Product 1

HCID 19843001HCID 19843001, compoundYield 87%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 6342AcetonitrileSolvent

Conditions

Temperature
90 °C

Procedure

2-Methylbenzylamine (0.5 mmol) was heated with catalyst Pd@ba-GO (10 mg) and solvent CH3CN (0.2 mL) at 90° C. in a flask open to air for 6 hours, and then stirred also at 90° C. under H2 gas (1 atm) for 6 hours to obtain di-(2-methylbenzyl)amine. Again, an unexpectedly high yield of 87% was observed.

Sources & evidence

ORD record
ord-8a636c60851447e3bb89c28e9fd60123
Source dataset
uspto-grants-2015_11
Patent number
US09180442B2

Reaction notes

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