反应详情

To a suspension of 3,5-dichlorophenol (0.6 g; 3.68 mmol) in H2O (15 ml), 30% H2O2 was added followed by I2 (0.47 g; 1.85 mmol). The resulting mixture was vigorously stirred for 8 h at room temperature, then extracted with CH2Cl2 (15 ml) and the organic phase was dried over anhydrous MgSO4 and filtered. The filtrate was evaporated under reduced pressure and the residue was purified by FCC (SiO2; CH2Cl2) to give the title compound (0.55 g; 52%) as colourless solid. 1H-NMR (CDCl3) 5.58 (s, 1H); 6.89 (s, 1H); 7.06 (s, 1H).

1. additionwas added
2. extractionextracted with CH2Cl2 (15 ml)
3. dry with materialthe organic phase was dried over anhydrous MgSO4
4. filtrationfiltered
5. customThe filtrate was evaporated under reduced pressure
6. customthe residue was purified by FCC (SiO2; CH2Cl2)