Hydrochloric Acid → HCID 118492323, compound

Participants

Reaction Steps

Ethyl 4-oxo-1-(3-(pyridin-3-ylthio)phenyl)-1,4-dihydropyridino[2,3-c]pyridazine-3-carboxylate (1.2 g, 3 mmol) was dispersed in 100 ml of methanol, KOH (840 mg, 15 mmol) was added, reacted at 40° C. for 4 h. The reaction solution was regulated with hydrochloric acid to pH 7, precipitated out solid, suction filtrated and dried to obtain an object product 200 mg.

Provenance & Evidence