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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 710770Generated: October 25, 2026

1-(2-Bromoethyl)-4-chlorobenzene → 5-(4-chlorophenethyl)-7-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/710770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromoethyl)-4-chlorobenzeneHCID 23029—
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactantm-Chlorophenylhydrazine hydrochlorideHCID 75331—
SolventTriethylamineHCID 8471—
Product5-(4-chlorophenethyl)-7-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indoleHCID 57876271—

Reaction Steps

The title compound is prepared by following Method 8 by using 1-(2-bromoethyl)-4-chlorobenzene, 3-chlorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181240B2
Source datasetuspto-grants-2015_11
ORD IDord-072695c4e1f248d1a8c8ac046220c56d
Source noteuspto-grants-2015_11