反应详情

A mixture of EXAMPLE 1A (6.2 g, 15.0 mmol) and OXONE® (92 g, 150 mmol) in ethyl acetate (350 mL) was stirred at 77° C. for 2 days. The mixture was filtered and the solids were washed with dichloromethane and concentrated to give the title compound.

1. filtrationThe mixture was filtered
2. washthe solids were washed with dichloromethane
3. concentrationconcentrated