HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Coumaric Acid → HCID 178511829, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Coumaric Acid | HCID 637542 | — |
| Reactant | Sitagliptin | HCID 4369359 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178511829 | HCID 178511829 | — |
Reaction Steps
Sitagliptin free base (2.0 gms) and coumaric acid (0.80 gms) were dissolved in Tetrahydrofuran (100 ml) at 60° C. to 65° C. and the resultant solution left for slow solvent evaporation at room temperature for 18 hours. Precipitated solids were filtered and dried at 50° C. to 55° C. for 6 hours to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181256B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-fab031baf009491885169999dab0ca6a |
| Source note | uspto-grants-2015_11 |