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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 711263Generated: October 25, 2026

(2-Methoxypyridin-4-yl)methanamine → 4-(Aminomethyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/711263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Methoxypyridin-4-yl)methanamineHCID 16227983—
SolventHydrochloric AcidHCID 313—
Product4-(Aminomethyl)pyridin-2(1H)-oneHCID 15079301—

Reaction Steps

The starting material (2-methoxypyridin-4-yl)methanamine 56-2 in 3N HCl was refluxed at 110° C. for 12 hours. The reaction was taken to dryness by rotary evaporation to give crude 4-(aminomethyl)pyridin-2(1H)-one 56-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181235B2
Source datasetuspto-grants-2015_11
ORD IDord-0a0113fcf18d4c1b932891df2d2f6d59
Source noteuspto-grants-2015_11