HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (2',5-Dimethyl-3,4'-bipyridin-6-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | N-(2,4-dimethoxybenzyl)-1-(2',5-dimethyl-3,4'-bipyridin-6-yl)methanamine | HCID 67208701 | — |
| Product | (2',5-Dimethyl-3,4'-bipyridin-6-yl)methanamine | HCID 67208705 | — |
Reaction Steps
To the reaction vessel containing N-(2,4-dimethoxybenzyl)-1-(2′,5-dimethyl-3,4′-bipyridin-6-yl)methanamine 81-4 (0.54 g, 1.5 mmol) was added trifluoroacetic acid (2 mL). The reaction was stirred at room temperature for 2 hours. TFA was removed by rotary evaporation to give crude (2′,5-dimethyl-3,4′-bipyridin-6-yl)methanamine 81-5. MS m/z 214.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181235B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-fca9816e122f4deeb6e8ba457a926f37 |
| Source note | uspto-grants-2015_11 |