反应详情

温度

100 °C

The crude product N′-(7-bromoquinoxalin-2-yl)cyclopropanecarbohydrazide was dissolved in HOAc (5 mL) and then heated to 100° C. overnight. The solvent was removed under vacuum and the residue was washed with water and dried in vacuo to afford the title product 8-bromo-1-cyclopropyl-[1,2,4]triazolo[4,3-a]quinoxaline as yellow solid in 42% overall yield (100 mg). m/z 291 (M+H)+.

1. customThe solvent was removed under vacuum
2. washthe residue was washed with water
3. customdried in vacuo