N'-(7-bromoquinoxalin-2-yl)cyclopropanecarbohydrazide → 8-Bromo-1-cyclopropyl-[1,2,4]triazolo[4,3-a]quinoxaline

Participants

Reaction Conditions

Reaction Steps

The crude product N′-(7-bromoquinoxalin-2-yl)cyclopropanecarbohydrazide was dissolved in HOAc (5 mL) and then heated to 100° C. overnight. The solvent was removed under vacuum and the residue was washed with water and dried in vacuo to afford the title product 8-bromo-1-cyclopropyl-[1,2,4]triazolo[4,3-a]quinoxaline as yellow solid in 42% overall yield (100 mg). m/z 291 (M+H)+.

Provenance & Evidence