Chlorosulfamic acid → HCID 67400524, compound

HRID 711688Notes

Reaction equation

HRID 711688 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[C:4]#[N:5].[S:14](Cl)(=[O:17])(=[O:16])[NH2:15]>>[C:4]([C:3]1[CH:6]=[C:7]([C:10]([F:11])([F:12])[F:13])[CH:8]=[CH:9][C:2]=1[NH:1][S:14]([NH2:15])(=[O:17])=[O:16])#[N:5]

Participants

3

Reactant 2

HCID 24499Chlorosulfamic acidHCID 126273614-Amino-3-cyanobenzotrifluoride

Product 1

HCID 67400524HCID 67400524, compound

Procedure

Prepared as in Example 77a from 2-amino-5-(trifluoromethyl)benzonitrile (Example 86b) and sulfamoyl chloride. 1H NMR (400 MHz, DMSO-d6) δ 7.53 (s, 2H), 7.74-7.76 (d, J=8.4 Hz, 1H), 8.01-8.03 (dd, J=8.4 Hz, 1.6 Hz, 1H), 8.23-8.233 (d, J=1.2 Hz, 1H), 10.16 (b, 1H).

Sources & evidence

ORD record
ord-305883dec0aa4c4fbe575b37048cd825
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

Loading…