3-Methoxy-1-propanol → HCID 67400006, compound

HRID 711788Notes

Reaction equation

HRID 711788 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][OH:6].[N+:7]([C:10]1[CH:17]=[CH:16][CH:15]=[C:14]([N+]([O-])=O)[C:11]=1[C:12]#[N:13])([O-:9])=[O:8]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][O:6][C:14]1[CH:15]=[CH:16][CH:17]=[C:10]([N+:7]([O-:9])=[O:8])[C:11]=1[C:12]#[N:13]

Participants

3

Reactant 2

HCID 741163-Methoxy-1-propanolHCID 520718Dinitrobenzonitrile

Product 1

HCID 67400006HCID 67400006, compoundYield 63.6%

Procedure

Prepared as in Example 111c from 3-methoxypropan-1-ol and 2,6-dinitrobenzonitrile in 63.6% yield. 1H NMR (400 MHz, CDCl3) δ 2.16 (m, 2H), 3.36 (s, 3H), 3.63 (t, J=5.6 Hz, 2H), 4.29 (t, J=6.4 Hz, 2H), 7.35 (dd, J=8.8, 0.8 Hz, 1H), 7.69 (t, J=8.8 Hz, 1H), (dd, J=8.4, 0.8 Hz, 1H).

Sources & evidence

ORD record
ord-d7a45cdfd29a43c9a04925e31811d176
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

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