Ethylamine → HCID 12715772, compound

HRID 711896Notes

Reaction equation

HRID 711896 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:5]=1[C:6]#[N:7])([O-])=O.[CH2:15](N)[CH3:16]>C1COCC1>[CH2:15]([NH:1][C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:5]=1[C:6]#[N:7])[CH3:16]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 520718Dinitrobenzonitrile

Product 1

HCID 12715772HCID 12715772, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared as in Example 90c from 2,6-dinitrobenzonitrile and a 2M ethylamine solution in THF in 88% yield. 1H NMR (400 MHz, DMSO-d6) δ 1.13 (t, J=7.6 Hz, 3H), 3.26-3.33 (m, 2H), 6.59 (bt, J=5.2 Hz, NH), 7.22 (d, J=9.2 Hz, 1H), 7.42 (d, J=8.0 Hz, 1H), 7.60 (t, J=8.4 Hz, 1H). MS 162 (M-Et).

Sources & evidence

ORD record
ord-cc5a63f5f7be4ea7ab3c7ef747d9c58c
Source dataset
uspto-grants-2015_11
Patent number
US09181276B2

Reaction notes

Loading…