3,4-Dihydro-2H-pyrano[3,2-b]pyridine → HCID 68842904, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3,4-dihydro-2H-pyrano[3,2-b]pyridine (0.60 g) in glycol monomethyl ether was added a catalytic amount of 10% Pd/C. The reaction mixture was stirred at 70° C. for 3 hours under H2 (2 MPa) and filtered. The filtrate was concentrated in vacuo to give the title compound as colorless oil (0.56 g, 90.00%), which was used for the next step without further purification. The compound was characterized by the following spectroscopic data: MS (ESI, pos. ion) m/z: 142.2 (M+1).

Provenance & Evidence