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HRID712819

反应详情

EQUATION

反应方程式

HRID 712819 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCCC[C@@H]1C(=O)O
HCID688618

(2R)-1-(tert-Butoxycarbonyl)piperidine-2-carboxylic acid

C11H19NO4

结构：COC(=O)c1ccc(C2(N)CC2)cc1.Cl
HCID66824369

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3C(=O)OC(C)(C)C)CC2)cc1
HCID86731619

未命名化合物

收率 78.2%

PROCEDURE

实验过程

The title compound (D53) (650 mg) was prepared according to the general procedure for amides preparation (Method A) starting from (R)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid (500 mg, available from Sigma Aldrich #516341), and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (470 mg). Reaction time: 18 hrs.

WORKUP

后处理

  1. customReaction time
  2. custom18 hrs