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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712820Generated: October 31, 2026

1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → HCID 117966958, compound

https://huagongshe.com/reaction/712820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
Reactant(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 57462942—
ReactantHCID 71187300HCID 71187300—
ProductHCID 117966958HCID 11796695827.4%

Reaction Steps

The title compound (D57) (25 mg) was prepared according to the general procedure for amides preparation (Method A) starting from 6-(tert-butoxycarbonyl)-5-methyl-6-azaspiro[2.5]octane-5-carboxylic acid (D6) (57 mg) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (46 mg). EDC.HCl: 1.1 eq, Reaction time: 48 hrs.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-11b4e3d3352b48c986b23fb1e562d95e
Source noteuspto-grants-2015_11