HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 89350949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | 2-Methylpiperidine-2-carboxylic acid | HCID 13205597 | — |
| Product | HCID 89350949 | HCID 89350949 | — |
Reaction Steps
The title compound (D79) (70 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-2-methylpiperidine-2-carboxylic acid (D47) (60 mg) and 4-(Trifluoromethyl)benzyl bromide (0.126 ml). (Na2CO3: 8 eq; reaction time 48 hrs; 68° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-08f8e865b3d74e9ebb9b3eea3275ab08 |
| Source note | uspto-grants-2015_11 |